"Post-operatively, corneal complications occurred in 11 (11%) of eyes: 4 eyes had non-healing epithelial defects (1 progressed to corneal ulcer and required penetrating keratoplasty (PKP)), 2 failed PKs required repeat grafts, 2 eyes developed corneal oedema associated with ocular hypertension and 3 eyes developed band keratopathy (BK). Among the eyes with BK, two had SO in the anterior chamber pre-SO removal and one had residual SO in the anterior chamber after SO removal (<10%); one of the three had mild BK before SO removal. Cystoid macular edema was seen in two eyes (2%) that had undergone RD repair; none of the patients was diabetic and none had CME pre-operatively. Seven eyes (7%) underwent PPV after SO removal: five for recurrent RD, one for full thickness macular hole without RD and one for hypotony (and underwent two PPV for this condition).
Hypotony, defined as IOP < 6 mm Hg on two or more occasions was observed in 8 (8%) eyes after SO removal. Average IOP pre-oil removal surgery was 16.1 mm Hg. None of the eyes had an average IOP < 6 mm Hg prior to SO removal, but 7 eyes had random measurements of IOP < 6 mm Hg before SO removal. Of these seven eyes, hypotony was seen in four eyes (57%) after SO removal. The average IOP in the four eyes that had lower IOP pre-SO removal and developed hypotony, was 7.4 mm Hg. Of the eight eyes developing hypotony after SO removal, four had open globe injury, three had advanced diabetic TRD and one had RRD with PVR. Of these hypotonus eyes, three had undergone retinotomy and retinectomy: two had 360° of retinotomy and retinectomy; one had a 90° retinotomy. Late hypotony (i.e., onset more than 6 months after SO removal) occurred only in one case, whereas seven eyes developed hypotony immediately after SO removal that persisted until last follow-up. One eye required reinsertion of oil for hypotony management. Pre-operative average VA of these eight hypotonus eyes was finger counting. No eyes progressed to phthisis.
Ocular hypertension, defined as IOP > 24 mm Hg on 2 or more occasions, was noted in 13 (13%) of eyes after SO removal. Two had Ahmed tubes inserted eventually after maximal therapy was reached at 15.2 and 4.3 months, respectively.
Retinal re-detachment occurred in seven eyes (7%), requiring a repeat vitrectomy with gas or oil tamponade: two were macular hole-related RDs. Recurrent RD occurred at an average of 5.6 months (range: 1–16 months) after SO removal. Five of the seven eyes that re-detached had received supplementation of demarcation laser at the time of SO removal. The indication for the initial PPV in these seven eyes included open globe injury (two eyes), diabetic TRD (one eye), combined RRD/TRD with PVR (one eye) with history of a failed PPV/gas and RRD (three eyes). Vitreous substitute used included one C3F8, one SF6 and rest with water.
One diabetic eye had new onset rubeosis after SO removal and underwent one anti-VEGF injection with rubeosis resolution.
Three eyes (3%) underwent membrane peel at the time of SO removal. The pre- and post-SO removal visual acuities in these three eyes were CF, 20/80, HM, and HM, 20/30, LP, respectively. The eye with final VA of LP vision developed hypotony after SO removal.
A total of 68% had cataract progression SO removal. A cataract was considered significant if lens had at least 3 + NS or 2 + PSC, or if the lens was described as mature, brunescent or white. Significant cataract progression was seen in 68 eyes (68%) in our series; 8 were described as mature, including 3 white and 5 brunescent cataracts."