Retinal angiomatous proliferation: 'Rap', type 3 wet Age Related Macular Degeneration (ARMD)
type 3 CNV, a rap: the choroidal vessels and retinal vessels join up (anastamose)
A RAP (retinal angiomatous proliferation) is a type of wet ARMD. It does not respond as well to antiVEGF treatment as the other types.
- text multifocal Retina 20
- 25% good response Retina17
- mean timme of recurrence was 5 months after the 3rd injection Retina17
- Eye 15
- Retina 16 OCT "subfoveal choroidal thickness <200 μm, presence of intraretinal fluid accumulation, absence of subretinal fluid, gently-sloping dome-shaped retinal pigment epithelial detachment or trapezoid-shaped retinal pigment epithelial detachment without an obvious peak, and intraretinal mass lesion"
- beginning with Retina15 "the earliest sign of Type 3 neovascularization is punctate hyperreflective foci above the external limiting membrane. The mature Type 3 lesions and associated serous pigment epithelial detachments are highly responsive to anti-vascular endothelial growth factor therapy"
- During treatment 5% of patients developl submacular haemorhages, and 5% rips Retina18